Circumcision reduces risk of HIV by half
Reasons cannot be found in sexual behaviour
but in the high infection potential of the foreskin [1]
Circumcision of men can reduce the risk of an AIDS infection by
half and therefore become an effective instrument against spread of this low
immunity syndrome. This is shown by examinations in Kenya and Uganda with
circumcised and uncircumcised men that have been published at December 12th 2006
in Washington by US Institute of Allergy and Infectious Diseases (NIAID). [2]
Circumcision not only can reduce the personal infection risk but hopefully the
spread of AIDS in society as well, Anthony Fancy, director of the Institute of
Allergy and Infectious Diseases at NIH, declared. [3]
According to this 2784 men in Kenya, that hadn't been infected by the virus at
first, were observed. At the end the number of AIDS infected and circumcised men
was lower than the number of not circumcised by around 53%. It is similar in
Uganda were 4996 men had been included. The risk of an infection decreased to
48% with circumcised men. [2]
The studies that were issued Wednesday determine the observations that had
already been done in the 1980s. Moreover an examination 2 years ago (2005) in
South Africa, testing 3035 sexually active men, concluded that men are protected
against HIV infections by about 65% after a circumcision had been done. [9]
The UN population programme estimates that by introducing circumcisions to
campaigns against AIDS in the following two decades 3.7 million infections and
2.7 million deaths could be avoided. [2]
A circumcision reduces the risk of infections of men with the virus HIV to one
sixth. This is what researchers of John Hopkins University in Baltimore
(Maryland) and the Indian AIDS Research Institute in Pune have concluded from a
study on Indian men. 2300 men were examined for about 7 years (1993-2000).
Circumcised men suffered a lot less from infections, said researcher Bollinger
and his colleagues in a scientific journal named „The Lancet“ (vol. 363, p. 1039
of March 26th 2004).
According to the study the foreskin is peppered with cells that are very
vulnerable to the AIDS virus. CD4+-T-lymphocytes and Langerhanssche cells are
two of those. The malicious AIDS virus is able to „easily slip in“ the
researchers explain. [4]
According to an Australian publication the risk of an infection of an
uncircumcised man is even up 8 times higher. It again determines: The virus
attacks certain cells on the inside of the male foreskin. Researchers of the
Woman's Hospital of University Melbourne found out after the evaluation 40
former studies that there are cells with HIV receptors on the inside of the male
foreskin. This is what makes this area highly vulnerable. [6]
Latterly the mini surgery that is known in Africa is not just initiation ritual
but that makes boys to men anymore. There now are even boys at those archaic
clan ceremonies whose families had never practiced circumcision before. Like
that the parents want to avoid that a little skin is going to be the reason for
deathly fate: The sons are being protected against HIV infection while having
sex.
The US virologist Bruce Patterson believes that he observed how those viruses
get into the body by passing the anatomic weak spot. He infected about 30
freshly removed foreskins with the deathly virus in vitro.
The researcher received fresh supply from men of an elder age that were forced
to give away their most private tissue due to phimosis. That way he got hold of
foreskins of men of the most vulnerable group of 20 to 45 year olds. Each time
new tissues arrive at his laboratory at the North-Western University of Chicago
Patterson marks the foreskin cells and AIDS viruses with different dyestuffs. If
now the viruses infiltrate the skin layers at the inside of the foreskin the
tissue discolours visibly - however, at the outside of the foreskin the viruses
simply roll off like drops off an umbrella.
Researchers have calculated for uncircumcised men that the infection rate rises
by 2.5 to 8 times compared to men without foreskin. Men with foreskin therefore
canker more easily with the AIDS virus. Medics thus advise circumcision.
Virologist Patterson is convinced: „Circumcision would be the best prevention
against AIDS in a lot of countries.“
Especially in Africa this recommendation could save lives: The Virus mainly
spreads by sexual intercourse between man and woman. 70 per cent of all HIV
infected people live south of the Sahara but only 10 per cent of all people
world wide.
Even scientists have made interesting discoveries in Africa lately. In Uganda
doctors tested 187 highly unequal pairs: While the women have already been
infected with the Virus the husbands have been untroubled. The scientists
enlightened the men about their high sex risk and gave away condoms for free.
The efforts of the doctors were in vain. Almost all set the warnings at nought.
But 2,5 years later surprisingly none of the 50 men had been infected by the
malicious virus - but 57 men that were not circumcised did.
Such epidemiologic investigations inspire the doctors to make speculative
calculations. In countries like Nigeria or Indonesia were only a short fifth of
all men are not circumcised the number of HIV infection could be reduced by 25
per cent the epidemiologist Robert Bailey of the University of Illinois in
Chicago shows. And in Zambia or Thailand - only every fifth men lives without
foreskin - the spread of the virus could be reduced by half if all men would
undergo circumcision [5]
Robert Bailey of the University Illinois in Chicago thus demands the consequent
circumcision of men in Asia and Africa. That way the rapid spread of AIDS shall
be stopped.
The AIDS expert Richard Burzynski disagrees with his colleagues; a circumcision
campaign would be too expensive. The costs of 4.50 Euros a man would overstrain
the health systems of these countries. Only 3 Euros at an average are being
spent per person and year. [7]
The two biggest anti HIV programmes, President Bush' „Emergency Plan for Aids
Relief“ and the „Global Fund to Fight Aids“ now declared to be read to finance
programmes like that [8].
According to the UNICEF in the African kingdom Swaziland more than 40% of all
adults are infected with the HIV virus, it is almost half of all 20 to 30 year
olds. By that the country has the highest quote world wide. To reduce the number
of new infections in the future doctors and government focus on the circumcision
of all sexually mature men. Tests with this kind of prevention in Kenya and
Uganda showed that by that the risk of infection can be reduced by half.
The health department of the country therefore considers a wide circumcision
campaign. However, they wait for a signal of the World Health Organisation. Not
because they need further scientific proof but because they urgently need
international help with the realisation. There are only 100 doctors for over one
million people in the African kingdom, which means that there are about 10000 to
11000 patients per doctor. And even if those are not only men a campaign like
the government plans cannot be executed like that.
At each „Circumcision-Day“, where hospitals offer free circumcisions, about 40
man can be treated; about 200 men have to go back home without surgery.
At the same time the enthusiasm for the „snip“ has been increasing lately. In
the first phase a lot of men refused as they were afraid of a deficit of their
esteem or weren't even informed appropriately. The problem was that in
Swaziland, contrarily to other South African countries, circumcision is not part
of an old tradition. One king of the Swazi prohibited the ritual in the 19th
century as the healing process had kept away the young men from military for too
long. It is the women that are responsible for the „boom“ of the last month that
forced their men and sons increasingly to visit the doctor to protect them and
themselves. To be able to cope with the rush the health department will focus on
the highly vulnerable group of 15 - 30 year olds and looks for help on an
international basis for the other males. „With a little help we could do the
biggest part of the campaign within a few years“ the doctors argue. Above that a
positive side effect is the enlightenment of the public about the exact
coherences of the disease. „We know that we haven't invented the silver ball
against Aids“ the organisers of the campaign say.
But if there is a cheap, safe and long term method to save the lives of
thousands of Swazi they are ready to do a nation wide „snip“. [10]
References:
[1] = „Der Spiegel„ Online, 26.03.2004 („Beschneidung schützt vor Aids„)
[2] = AFP, 13.12.2006 („Beschneidung von Männern senkt Aids-Gefahr deutlich„)
[3] = Sueddeutsche, 14.12.2006 („Kampf gegen Aids„)
[4] = dpa / The Lancet, 1999, Bd. 363, S. 1039 („HIV-Risiko durch Beschneidung
bei Männern auf ein Sechstel reduziert„)
[5] = Der Spiegel, 15.01.2001 („Männer mit Vorhaut stecken sich leichter mit dem
Aidserreger an„)
[6] = Der Spiegel, 2000 („Beschnittene Männer haben geringeres HIV-Risiko„)
[7] = Münchener Abendzeitung, 30.09.1999 („Kleineres Aids-Risiko für
Beschnittene„)
[8] = Der Tagesspiegel of 15.12.2006 („Beschnittene Männer haben geringeres
Aids-Risiko„)
[9] = Medica.de, 28.07.2005 ("HIV: Beschneidung verhindert viele Infektionen")
[10] = Berliner Umschau of 05.02.2007 („Aids-Prävention: Swasiland plant den
„Snip" für alle„)
Latest actualisation: 01.10.2007
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